About…Individual Test Pathophysiology
Twenty-seven (27) analytes of Biochemical Analysis are listed on the following web pages in alphabetic order. The statements made concerning the bioanalytes or lab tests have been orientated with nutritional assessment as the premise. General descriptions of the lab test have been compiled from the public domain of medical information and applied to the unique requirements of Healthlab. The conditions for decreased and increased concentrations are general in nature, but orientated around nutritional health processes. The conditions listed are not conclusive, but do reflect as accurately as possible the scope of Preventive Care. Since this type and caliber of routine report is unprecedented, professional input is strongly recommended for this report is not intended as a practice of clinical pathology.
NONDISEASES SOURCES OF CONCENTRATION VARIATION
FASTING: Fasting is the standard condition for Healthlab© Health and Nutrition Assessment Survey (HANES). A fast of twelve (12) hours, but no more than sixteen (16) hours is recommended for patient standardization.
EATING: Ingestion of food up to 4 - 6 hours will compromise the standardization for the analytic interpretation. Water is encouraged. Do not dehydrate yourself prior to having your blood taken but maintain water intake during the 12 hours of fasting.
EXERCISE: Vigorous to strenuous physical exercise can greatly effect homeostasis of glucose, lactate, glycerol, hormones, and muscle enzymes. A general physiologic rule follows: the degree to which an individual is out-of-shape, the greater the elevations in muscle enzymes are found in your blood.
ALCOHOL: Long and short-term effects of alcohol use are demonstrated: such as hypoglycemia, elevated uric acid and triglycerides and dehydration.
COFFEE: Coffee stimulates increases of cortisol, catecholamaines such as epinephrine also known as adrenaline, dopamine acting as hormones or neurotranmitters derived from the amino acid, tyrosine and non-esterified fatty acids.
TOBACCO: Smoking compromises homeostatic catecholamines (adrenaline) and cortisol. Most individuals find this restriction intolerable for Healthlab© requirements of standardization. Notation of smoker or non-smoker is made and may effect the database for healthy status.
POSTURE: Usually variation occurs between sitting briefly for venipuncture and prolonged lying in bed. Most individuals for this survey are healthy ambulatory.
DRUGS: There are well over 30,000 medications and drugs that can effect some metabolic parameters. Medication history is important for appropriate interpretation of lab tests.
HEALTH: The Health-Associated Reference Interval is statistically applied when pathophysiologic overlap (borderline condition) between ± HAD 2 - 3 exist. This effects approximately 4.5% of a reference population and care must be exercised to include intra-variation in this interval of overlapping health status.